Factors Affecting Hemoglobin A1c Values
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According to the World Health Organization, more than 220 million people worldwide have diabetes, and this number is likely to more than double by 2030 without intervention. Diabetes is the seventh leading cause of death worldwide as reported by the American Diabetes Association. Hemoglobin A1c is recognized as effective in monitoring long- term glycemic control for improved diabetes management. While clinical assessment of hemoglobin A1c values is critical, an understanding of performance metrics and the effect of clinical conditions, pharmacokinetics, and hemoglobin variants on hemoglobin A1c values need to be fully realized for optimal clinical utilization and reduced risk for complications.
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