Molecular Components and Insect Venom Allergy: Shifting towards a New Testing Paradigm
Dr. Markus Ollert
Professor of Molecular Dermatology and Immunology
Department of Dermatology and Allergy
Head of Clinical Research Group of Molecular Dermatology and Immunology/ZAUM
Munich University of Technology
According to the 2011-2012 WAO White Book on Allergy, hymenoptera venom allergy (HVA) is a common global medical problem and refers to subjects who have a sting-induced large, local (LL) or a systemic allergic reaction (anaphylaxis). The morbidity rate for HVA is underestimated as fatal reactions may not be appropriately recorded. The incidence of positive specific IgE antibodies to venom is high in the general population, and it has been documented that fatal reactions occur in up to 50% of individuals who have no documented history of a previous systemic reaction. The use of venom molecular allergens can help allergists define a more personalized and relevant sensitization profile for each patient. Thus, venom molecular allergens help the clinician to choose the right venom immunotherapy for the patient. In addition, venom molecular allergens are ideal tools to differentiate in patients with double-sensitization to honey bee and vespid species. Finally, as some allergens are underrepresented in classical assays based on extracts, venom molecular allergens increase the assay sensitivity of specific IgE tests in HVA.
Attendees of this webinar will:
- Learn about insect venom allergy and the main eliciting allergens
- Identify the critical factors of in vitro diagnosis of insect venom allergy
- Understand the clinical utility and benefits of molecular allergen components for the diagnosis of insect venom allergy
- Discover new in vitro diagnostic algorithm for insect venom allergy based on crude extracts and molecular components.
This program has been designated for 1.0 PACE continuing education credit.*
*There is a charge of $10.00 plus local tax for each half or full hour of CE credit. Purchase of CE credit is optional. Non-accredited customer participation in Siemens educational offerings and programs remains complimentary.