The Role of TSI Testing in the Diagnosis of Graves’ Disease
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The Role of TSI Testing in the Diagnosis of Graves’ Disease

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Manjula Gupta, PhD
Professor of Pathology and Medicine, CCI College of Medicine
Medical Director, Endo/Immunology Labs Clinical Pathology, Cleveland Clinic

Graves’ disease is an autoimmune disorder that leads to overactivity of the thyroid gland. It is the most common cause of hyperthyroidism. Graves’ disease is 5-10 times more prevalent in women than men and affects 2-5% of all women. Left untreated, Graves’ disease can lead to miscarriage, birth defects, thyroid eye disease, and can be life-threatening. Proper diagnosis is crucial to ensure the appropriate treatment is administered as soon as possible.

The thyroid stimulating immunoglobulin (TSI) is an autoantibody that causes Graves’ hyperthyroidism. The TSI assay has been proven to have high specificity and sensitivity, aiding in the differential diagnosis of Graves’ disease.

This webinar will focus on Graves’ disease diagnosis and monitoring, and will provide detailed information on the TSI assay, including relevant case studies.

Learning Objectives

  • Provide an overview of thyroid autoimmunity with focus on Graves’ disease
  • Summarize current assay techniques for measuring TRabs (TBII and TSI)
  • Describe the differences in the utilization of the TBII and TSI assays
  • Discuss the benefit of incorporating the TSI test in the differential diagnosis of Graves’ disease

This program has been designated for 1.0 PACE continuing education credit.*

*There is a charge of $10.00 plus local tax for each half or full hour of CE credit. Purchase of CE credit is optional. Non-accredited customer participation in Siemens educational offerings and programs remains complimentary.

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